Chemical Peels in Skin of Color: A Scoping Review of Safety, Efficacy, and Practice Patterns

Chemical peels are widely used for both cosmetic and medical dermatologic indications, but their application in individuals with skin of color (Fitzpatrick skin types IV-VI) requires caution due to the increased risk of pigmentary complications. To assess their safety and efficacy, a comprehensive PubMed review was conducted, identifying 473 studies, seven of which met the inclusion criteria, specifically those articles documenting chemical peels in skin of color populations and reported primary outcomes. Among the seven included studies, five evaluated peels for the treatment of acne and acne scarring, all reporting positive outcomes with minimal adverse effects. One study addressed lichen planus pigmentosus, showing significant clinical improvement, and one highlighted chemical burns resulting from improper use. Overall, superficial peels such as glycolic and salicylic acid show promise for acne and pigmentary disorders with good safety profiles. However, research is limited by small sample sizes, short follow-ups, and underrepresentation of Fitzpatrick skin types IV-VI. Further research is needed to establish standardized protocols, assess deeper peels, and guide equitable, evidence-based care.