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Updated: Jun 19, 2026
Generation of ESC-derived Mouse Airway Epithelial Cells Using Decellularized Lung Scaffolds
Published on: May 5, 2016
Generation of the mouse ESC line from NOD-scid gamma mouse
Yu Wang1, Suzilong Meng1, Zezhong Su1
1Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510275, China.
Abstract:
We have established mouse embryonic stem cells (mESCs) from the embryos of NOD-scid gamma mice. These mESCs exhibit robust pluripotency and differentiation potential. EB differentiation assays demonstrate significant expression of markers from all three germ layers, and karyotpe analysis confirmed their chromosomal stability. Given the strong differentiation capacity of these mESCs, the cell line established in this study can provide a valuable cellular model for research on immune-related diseases.
