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Updated: Jun 19, 2026

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
Published on: May 11, 2015
Portopulmonary Hypertension: Current Perspectives
Teresa John1, Rudolf E Stauber2, Philipp Douschan1
1Division of Respiratory Medicine, Lung Research Cluster, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Abstract:
Portopulmonary hypertension (PoPH) is a form of pulmonary arterial hypertension in the setting of cirrhotic or noncirrhotic portal hypertension. It is a significant complication affecting approximately 5% of patients with cirrhosis. PoPH contributes to morbidity and mortality of chronic liver disease by significantly increasing right cardiac afterload, ultimately leading to right heart failure and complicating disease management. We review the current literature of PoPH pathophysiology with special focus on cardiopulmonary hemodynamics, clinical presentation, diagnostic challenges, and management strategies. A central illustration should visually capture the summarized information.
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