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Updated: Jun 19, 2026

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

Developing stem cell-based bovine embryos for in vitro breeding.

Zongliang Jiang¹

¹Department of Animal Sciences, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32610, USA.

The Journal of Reproduction and Development

|June 17, 2026

Summary

This summary is machine-generated.

Bovine blastoids, stem cell-derived embryo models, offer new insights into early embryogenesis and advanced reproductive technologies for cattle. This technology shows promise for in vitro breeding and enhancing reproductive efficiency.

Keywords:

ART Blastoid Bovine Embryo In vitro breeding Stem cells

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Area of Science:

Reproductive Biology
Developmental Biology
Stem Cell Science

Background:

Stem cell-based embryo models, or blastoids, replicate early embryogenesis.
These models offer novel avenues for understanding developmental processes.
Applications in assisted reproductive technologies (ARTs) are emerging.

Purpose of the Study:

To review bovine pluripotent stem cells, including embryo-derived and induced pluripotent stem cells.
To explore current advancements in generating bovine blastoids.
To discuss the potential applications of bovine blastoid technology in cattle breeding and reproductive efficiency.

Main Methods:

Summarizing existing literature on bovine pluripotent stem cells.
Reviewing techniques for creating bovine blastoids from stem cells.
Analyzing the potential applications and challenges of blastoid technology in cattle.

Main Results:

Bovine pluripotent stem cells, including embryo-derived stem cells and induced pluripotent stem cells, are summarized.
Progress in generating bovine stem cell-derived embryos (blastoids) is detailed.
Potential applications in in vitro breeding and reproductive efficiency are explored.

Conclusions:

Bovine blastoid technology represents a significant advancement in understanding early embryogenesis.
This technology holds promise for enhancing reproductive efficiency in cattle through in vitro breeding.
Further research is needed to overcome challenges and fully realize the potential of bovine blastoids.