Related Experiment Video
Updated: Jun 19, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
[A practical guide to the diagnosis of complex regional pain syndrome]
François Luthi1,2, Michel Konzelmann3
1Département de réadaptation de l'appareil locomoteur, Clinique romande de réadaptation Suva, 1950 Sion.
Abstract:
Complex Regional Pain Syndrome (CRPS), previously known as algodystrophy or Sudeck's disease, is a condition that occurs following trauma and affects the distal parts of the limbs. An early diagnosis is crucial for a favourable outcome. This diagnosis is based on the Budapest criteria, recently revised (Valencia Consensus). Any primary care physician (GPs or surgeons) can make the diagnosis, provided the criteria are applied rigorously and documented. Knowledge of the main differential diagnoses and identification of red flags helps avoid diagnostic delays and misdiagnosis in cases of unexplained pain. Despite the absence of biomarkers, a confirmed diagnosis can be reached through a combination of medical history, clinical examination, and judicious use of diagnostic tests.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Analgesia and Pain Management

