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Related Concept Videos

Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Frustration and Conflict: Avoidance-Avoidance, Double-Approach Avoidance01:14

Frustration and Conflict: Avoidance-Avoidance, Double-Approach Avoidance

Avoidance-avoidance conflict refers to a psychological situation where a person must choose between two or more unpleasant alternatives. These conflicts are particularly stressful because neither option is desirable. This dilemma is often expressed in sayings like "caught between a rock and a hard place" or "between the devil and the deep blue sea." For instance, individuals who fear dental procedures may find themselves torn between enduring a painful toothache or facing the anxiety of...
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

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Related Experiment Video

Updated: Jun 19, 2026

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
15:27

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

Published on: July 13, 2014

The Prenatal Dilemma: Fever vs Acetaminophen? Navigating a Difficult Choice.

Mohammad Darayesh1,2, Elaheh Entezar Almahdi3,4, Mirza Ali Mofazzal Jahromi3,4,5

  • 1Department of Dermatology, Shiraz University of Medical Sciences, P.O. Box: 71348 -14336, Shiraz, Iran.

ACS Pharmacology & Translational Science
|June 18, 2026
PubMed
Summary

Acetaminophen use in pregnancy for maternal hyperthermia is debated due to potential neurodevelopmental risks. This review suggests tailored prescribing based on specific indications to balance maternal and fetal health.

Keywords:
acetaminophen (paracetamol)hyperthermianeurodevelopmental disordersoffspringpregnancy

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Related Experiment Videos

Last Updated: Jun 19, 2026

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
15:27

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Published on: July 13, 2014

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05:33

Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting

Published on: August 4, 2023

Area of Science:

  • Obstetrics and Gynecology
  • Neuroscience
  • Pharmacology

Background:

  • Maternal hyperthermia poses significant risks to fetal development.
  • Acetaminophen is frequently used during pregnancy to manage fever.
  • Emerging research links prenatal acetaminophen exposure to neurodevelopmental disorders.

Purpose of the Study:

  • To examine the risk-benefit profile of acetaminophen for maternal hyperthermia during pregnancy.
  • To propose an updated prescribing strategy for acetaminophen in pregnant individuals.
  • To address the clinical challenge posed by potential neurodevelopmental risks.

Main Methods:

  • Literature review of existing studies on acetaminophen, maternal hyperthermia, and neurodevelopmental outcomes.
  • Analysis of risk-benefit data for acetaminophen use in specific pregnancy scenarios.
  • Synthesis of evidence to inform clinical practice guidelines.

Main Results:

  • The association between prenatal acetaminophen exposure and neurodevelopmental disorders requires careful consideration.
  • The benefits of treating maternal hyperthermia must be weighed against potential risks.
  • Current prescribing practices may not adequately account for these emerging risks.

Conclusions:

  • A nuanced, indication-specific approach to prescribing acetaminophen in pregnancy is warranted.
  • Clinicians should individualize treatment decisions based on the severity of maternal hyperthermia and gestational stage.
  • Further research is needed to clarify the causal relationship and refine clinical recommendations.