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Comparative Evaluation of Unilateral Recession-Plication Versus Bilateral Three-Muscle Surgery for Large-Angle
Kamlesh Anand1, Vaibhav Nagpal1, Paromita Dutta1
1Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.
Journal of Pediatric Ophthalmology and Strabismus
|June 18, 2026
Summary
For large-angle exotropia, a two-muscle surgery (unilateral recession-plication) is as effective as three-muscle surgery. Both methods achieve similar ocular alignment and patient-reported outcomes, offering comparable results for strabismus correction.
Area of Science:
- Ophthalmology
- Strabismus Surgery
- Pediatric Ophthalmology
Background:
- Large-angle exotropia presents a significant challenge in strabismus management.
- Surgical correction aims to restore binocular vision and improve cosmetic appearance.
- Traditional three-muscle surgery is often employed, but less invasive options are being explored.
Purpose of the Study:
- To compare the efficacy of unilateral recession-plication (two-muscle surgery) versus bilateral three-muscle surgery for large-angle exotropia.
- To evaluate ocular alignment, motor outcomes, and patient-reported quality of life.
Main Methods:
- A prospective, comparative study included 66 patients with large-angle exotropia (50-65 PD).
- Patients were divided into a two-muscle group (unilateral LR recession and MR plication) and a three-muscle group (bilateral LR recession and MR resection).
- The Adult Strabismus-20 (AS-20) questionnaire assessed outcomes pre- and post-operatively.
Main Results:
- Mean postoperative deviations were comparable: 9.29 ± 3.16 PD (two-muscle) vs. 8.44 ± 3.54 PD (three-muscle).
- Successful motor outcomes were achieved in 73.53% (two-muscle) and 75% (three-muscle) of patients.
- Both surgical approaches led to significant improvements in AS-20 scores with similar ocular motility limitations.
Conclusions:
- Unilateral recession-plication (two-muscle surgery) is an effective alternative for large-angle exotropia (up to 65 PD).
- It provides comparable motor outcomes and functional results to traditional three-muscle surgery.
- This approach offers a viable option with similar efficacy and limitations.