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Related Experiment Video

Updated: Jun 20, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Isolated Polyhydramnios: diagnosis should be made based on both elevated AFI and elevated MVP.

Alessandro Petrecca1, Vivian Nguyen2, Lauren Bracken2

  • 1Department of Woman and Child Health and Public Health Sciences, Fondazione Policlinico A. Gemelli IRCSS, Rome, Italy (Petrecca, Ghi).

American Journal of Obstetrics & Gynecology MFM
|June 18, 2026
PubMed
Summary

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This summary is machine-generated.

Isolated polyhydramnios poses risks, particularly when both amniotic fluid index (AFI) and maximum vertical pocket (MVP) are elevated, increasing adverse perinatal outcomes. However, any form of isolated polyhydramnios is linked to adverse maternal outcomes, mainly cesarean delivery.

Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Diagnostic Ultrasound

Background:

  • Isolated polyhydramnios, defined by elevated amniotic fluid index (AFI) or maximum vertical pocket (MVP), is common.
  • The association between different sonographic definitions of isolated polyhydramnios and adverse perinatal outcomes requires clarification.

Purpose of the Study:

  • To determine which sonographic definition of isolated polyhydramnios (AFI alone, MVP alone, or both) best predicts adverse perinatal outcomes.

Main Methods:

  • Retrospective case-control study of singleton pregnancies with isolated polyhydramnios versus controls.
  • Polyhydramnios defined as elevated AFI (≥24 cm) only, MVP (≥8 cm) only, or both.
  • Exclusion of pregnancies with multiple gestations, diabetes, oligohydramnios, or fetal anomalies.
Keywords:
amniotic fluid indexisolated polyhydramniosmaximum vertical pocketpolyhydramniosultrasound

Related Experiment Videos

Last Updated: Jun 20, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

  • Primary outcome: composite adverse perinatal outcome (CAPO); Secondary outcomes: adverse maternal outcome (CAMO), cesarean delivery.

    • Main Results:

    • Isolated polyhydramnios was associated with higher rates of cesarean delivery, large-for-gestational-age neonates, and macrosomia.
    • Only pregnancies with both elevated AFI and MVP were independently associated with CAPO, NICU admission, and perinatal death.
    • All diagnostic groups of isolated polyhydramnios were associated with increased odds of CAMO and cesarean delivery.

    Conclusions:

    • Adverse perinatal outcomes, including perinatal death and NICU admission, are significantly increased only when both AFI and MVP are elevated in isolated polyhydramnios.
    • Regardless of the sonographic criteria used, isolated polyhydramnios is independently associated with adverse maternal outcomes, primarily driven by an increased rate of cesarean delivery.