Related Experiment Video
Updated: Jun 20, 2026
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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
Published on: July 12, 2012
Nearest-neighbors assisted unsupervised analysis for methylation array profiling for central nervous system tumors
Mallika Gandham1, Surendra Dasari1, Cherisse Marcou2
1Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Brain Pathology (Zurich, Switzerland)
|June 18, 2026
Abstract:
The NN method identifies the five nearest reference dataset neighbors to a tested sample and provides an objective estimation of the tested sample methylation class cluster rather than relying on subjective visualization using dimensionality reduction methods such as UMAP and t-SNE.
