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Muscle Mass, Adiposity, and Bone Health in Surgical Care Setting: A Cross-Sectional Study
Ngo Thi Thu Thuy1, Le Van Thieu2, Tran Vuong The Vinh3
1Department of Internal Medicine, Hai Phong Medical University Hopspital, Hai Phong, Vietnam.
Journal of Bone Metabolism
|June 19, 2026
Summary
Skeletal muscle mass, especially in the trunk and hip, is key for bone mineral density (BMD). Adiponectin negatively impacts BMD, suggesting muscle assessment and metabolic factors are vital for surgical recovery.
Area of Science:
- Gerontology
- Orthopedics
- Metabolic Medicine
Background:
- Osteoporosis and sarcopenia significantly impact surgical outcomes and recovery.
- Understanding body composition and metabolic factors is crucial for perioperative risk assessment.
- This study investigates the link between regional body composition, adipokines, and bone mineral density (BMD).
Purpose of the Study:
- To evaluate the relationships between regional muscle mass, fat mass (FM), and circulating adipokines with BMD.
- To identify key predictors of bone mineral density (BMD) in a patient cohort.
Main Methods:
- A cross-sectional study involving 199 patients.
- Whole-body dual energy X-ray absorptiometry (DXA) assessed regional lean and FM and BMD.
- Serum leptin and adiponectin levels were measured; correlations and regression analyses were performed.
Main Results:
- Trunk and gynoid muscle mass strongly correlated with BMD (T-score).
- Adiponectin showed an inverse correlation with BMD.
- Trunk muscle mass, gynoid muscle mass, BMI, and adiponectin were independent predictors of BMD.
Conclusions:
- Skeletal muscle mass, particularly in the trunk and hip, is the primary determinant of bone density.
- Adiponectin negatively influences BMD, highlighting its role in bone health.
- Integrating muscle mass assessment and metabolic optimization into perioperative care may improve surgical outcomes and recovery.
