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Related Experiment Video

Updated: Jun 20, 2026

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Published on: December 23, 2014

Ultrasound-Based SECURED Protocol for Central Venous Catheterization: A Feasibility Study.

Moon Soo Choi1, Han Ho Do1, Jeong Hun Lee1

  • 1Department of Emergency Medicine, Dongguk University Ilsan Hospital, Goyang, Republic of Korea, dongguk.edu.

Biomed Research International
|June 19, 2026
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Summary

The SECURED protocol standardizes ultrasound use for central venous catheterization, improving safety and reducing complication detection time. This six-step POCUS workflow ensures efficient and effective patient care in critical settings.

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Area of Science:

  • Emergency Medicine
  • Critical Care
  • Point-of-Care Ultrasound (POCUS)

Background:

  • Central venous catheterization (CVC) is vital for critically ill patients but carries risks of mechanical complications.
  • Current ultrasound-guided (USG) CVC practices are often fragmented, limiting their full potential.
  • The SECURED protocol was developed to integrate POCUS into a standardized, six-step CVC workflow.

Purpose of the Study:

  • To evaluate the feasibility and effectiveness of the SECURED protocol for central venous catheterization.
  • To assess the protocol's completion rate and its impact on complication detection.
  • To compare the time efficiency of ultrasound-based complication detection with traditional chest radiography.

Main Methods:

  • A prospective observational study involving 109 adult patients undergoing internal jugular vein (IJV) CVC in the emergency department (ED).
  • The SECURED protocol includes pre- and post-procedure ultrasound scans of the IJV, pleura, and heart.
  • Primary endpoint: protocol completion rate. Secondary endpoint: time for complication detection via ultrasound vs. chest radiography.

Main Results:

  • The SECURED protocol demonstrated a 100% completion rate in all 109 cases.
  • The protocol identified pre-existing IJV thrombosis, prevented arterial punctures, and detected venous dissection.
  • Ultrasound-based detection of pneumothorax and catheter malposition was significantly faster (2.5 min) than chest radiography (12.4 min).

Conclusions:

  • The SECURED protocol offers a practical, time-efficient screening framework for CVC.
  • It standardizes POCUS use, enabling proactive risk detection and immediate post-procedural confirmation.
  • Further validation in larger studies may support broader implementation for improved clinical decision-making.