[Sepsis in the Intermediate Respiratory Care Unit: Restrospective Study]

Sepsis is a dysregulated response to infection that can lead to organ dysfunction and requires urgent management. Advanced respiratory support (high-flow oxygen therapy and/or non-invasive mechanical ventilation) has emerged as a therapeutic option in patients with respiratory failure.

To identify factors associated with therapeutic failure (defined as the need for invasive mechanical ventilation or death) in patients with respiratory sepsis treated in a respiratory intermediate care unit. A retrospective observational study including 47 patients admitted between January 2021 and December 2023 was conducted. Therapeutic failure was associated with elevated procalcitonin levels (p = 0.046). Lower PaO₂/FiO₂ ratios and the use of vasopressors were also associated with increased mortality (p = 0.007).

Advanced respiratory support could be considered a treatment option in this context. Elevated procalcitonin, hypoxemia at admission, and the need for vasopressors were associated with worse outcomes, although these findings should be interpreted with caution.