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Surgery for wrist osteoarthritis.

Mohammed Shaheen1,2, Brennen T McManus2, Vieda Lusa3

  • 1Stanford Medical School, Palo Alto, California, USA.

The Cochrane Database of Systematic Reviews
|June 19, 2026
PubMed
Summary

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This review protocol assesses partial wrist fusion versus sham surgery for non-inflammatory wrist osteoarthritis. It also examines other surgical options against non-surgical treatments or other surgeries.

Area of Science:

  • Orthopedic surgery
  • Rheumatology
  • Evidence-based medicine

Background:

  • Non-inflammatory osteoarthritis of the wrist significantly impacts patient quality of life.
  • Current surgical interventions for wrist osteoarthritis lack comprehensive comparative effectiveness data.

Purpose of the Study:

  • To evaluate the benefits and harms of partial wrist fusion compared to placebo or sham surgery in adults with wrist osteoarthritis.
  • To assess various surgical interventions (e.g., proximal row carpectomy, total wrist arthroplasty, wrist denervation) against control groups or alternative treatments.

Main Methods:

  • This study outlines a protocol for a Cochrane Review focusing on surgical interventions for wrist osteoarthritis.
  • Systematic review methodology will be employed to synthesize evidence from relevant randomized controlled trials and observational studies.

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Main Results:

  • This section will report findings on the efficacy and safety of partial wrist fusion and other surgical procedures.
  • Comparative data on benefits and harms across different surgical and non-surgical interventions will be presented.

Conclusions:

  • The review aims to inform clinical decision-making regarding surgical management of non-inflammatory wrist osteoarthritis.
  • Evidence synthesis will guide patients and clinicians in choosing the most effective and safe treatment options.