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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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Related Experiment Video

Updated: Jun 20, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

Multisystem Imaging Features and Organ Co-Occurrence in Children With Tuberous Sclerosis Complex.

Yan Tan1, Chengwen Guo1, Jingzhe Liu1,2

  • 1Department of Ultrasound, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.

Journal of Clinical Ultrasound : JCU
|June 19, 2026
PubMed
Summary
This summary is machine-generated.

Tuberous sclerosis complex (TSC) shows varied organ involvement. TSC2 mutations significantly increase the risk of kidney tumors and cysts compared to TSC1, impacting disease management.

Keywords:
clinical ultrasoundimagingpediatrictuberous sclerosis

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Area of Science:

  • Genetics and Molecular Biology
  • Medical Imaging
  • Pediatric Neurology

Background:

  • Tuberous sclerosis complex (TSC) exhibits diverse patterns of organ involvement.
  • Understanding genotype-specific disease expression is crucial for managing TSC.

Purpose of the Study:

  • To investigate differences in multiorgan involvement between TSC1 and TSC2 genotypes using imaging.
  • To elucidate the disease expression profile of TSC based on genetic mutations.

Main Methods:

  • Retrospective analysis of 112 pediatric patients with TSC.
  • Evaluation of clinical, imaging, and genetic data for brain, heart, and kidney involvement.
  • Comparison of organ involvement patterns between TSC1 and TSC2 mutations.

Main Results:

  • No significant differences in cerebral or cardiac involvement between TSC1 and TSC2 mutations.
  • Elevated risk of renal angiomyolipoma and renal cysts in patients with TSC2 mutations (p < 0.001 and p = 0.003, respectively).
  • Predominant phenotypes include isolated brain involvement and combined brain-heart-kidney involvement.

Conclusions:

  • Multisystem imaging heterogeneity in pediatric TSC is significant.
  • Co-occurrence analysis aids in predicting disease evolution.
  • Findings inform long-term clinical management strategies for TSC patients.