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Tranexamic Acid-Induced Seizure After Cardiopulmonary Bypass: A Case Report
Kaiki Oya1, Jun Maki2, Midoriko Higashi3
1From the Department of Anesthesiology and Critical Care Medicine.
A&A Practice
|June 19, 2026
Summary
High-dose tranexamic acid (TXA) can trigger seizures during cardiac surgery. Continuous EEG and ScvO2 monitoring are crucial for early detection and intervention of these seizures.
Area of Science:
- Anesthesiology
- Neurology
- Cardiac Surgery
Background:
- Tranexamic acid (TXA) is used in cardiac surgery but is a known risk factor for perioperative seizures.
- Diagnosing TXA-induced seizures is challenging due to anesthetic and muscle relaxant effects masking clinical signs.
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