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Updated: Jun 21, 2026
An Intra-Tissue Radiometry Microprobe for Measuring Radiance In Situ in Living Tissue
Published on: June 2, 2023
Development of In situ Dosimetry for FLASH Proton Radiotherapy via Organic Scintillating Fibers
Codey Olson1, Jacob Strong1, Adam Paxton2
1University of Utah Nuclear Engineering Program, Department of Civil and Environmental Engineering, 110 S Campus Dr., Suite 2000, Salt Lake City, UT, 84112.
Objectives:
This work presents the design, development, and initial proof of concept testing of a dosimetry device intended for FLASH radiotherapy.
Methods:
The system incorporates organic scintillating fibers coupled to a silicon photomultiplier (SiPM) and an FPGA-based readout, with fiber geometry optimized to minimize perturbations to a clinical proton beam, as confirmed through measurements at the Huntsman Cancer Institute (HCI).
Results:
Tests using a portable X ray unit demonstrated a strong correlation between integrated charge and delivered dose (up to ∼35 mrem s-1) and showed that the detector can respond on nanosecond timescales, enabling the potential for rapid safety interlock triggering with minimal latency.
Conclusion:
Preliminary proton irradiations at HCI further indicated that the device can resolve individual beam pulses, a capability valuable for both FLASH research and conventional radiotherapy.
Advances In Knowledge:
These results highlight the need for continued refinement of the experimental setup, readout electronics, and detector performance to fully realize real time, in situ dose and pulse monitoring.
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