Related Experiment Videos
Synthesis and activities of antitumor agents
Journal of Medicinal Chemistry
|March 1, 1979
Abstract:
N-(2-Chloroethyl)-N-nitrosocarbamoyl derivatives of glycosylamines have been prepared. Six N-(2-chloroethyl)-N-nitrosoureas, including three disaccharide derivatives, were submitted to a determination of antitumor activity. All the compounds tested exhibited strong antitumor activity against leukemia L1210 in mice.
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Association between excessive supraventricular ectopy and subclinical cerebrovascular disease: a population-based study.
European journal of neurology·2019
Prognostic factors for survival in cervical cancer patients with bone metastasis.
European journal of gynaecological oncology·2015
Associations of HLA class I alleles in Japanese patients with Crohn's disease.
Genes and immunity·2014
Ectopic cardiovascular fat in middle-aged men: effects of race/ethnicity, overall and central adiposity. The ERA JUMP study.
International journal of obesity (2005)·2014
Discovery of TL10: A Soluble and Long-Acting MC4R Agonist with Tunable Lipidation for Sustained Pharmacological Activity.
Journal of medicinal chemistry·2026
Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.
Journal of medicinal chemistry·2026
Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.
Journal of medicinal chemistry·2026
Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.
Journal of medicinal chemistry·2026
Neutrophil Elastase-Responsive Linkers for Precision Antibody-Drug Conjugates.
ACS medicinal chemistry letters·2026
Supramolecular Site-Specific Antibody Drug Conjugates Outperform Cysteine-Conjugated Analogs in Pancreatic Peritoneal Carcinomatosis.
bioRxiv : the preprint server for biology·2026