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Corrigendum to "Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the

Subir Roy Chowdhury1, Jelena Djordjevic1, Ella Thomson1

  • 1Division of Neurodegenerative Disorders, St Boniface Hospital Research Centre, Winnipeg, MB, R2H 2A6, Canada.

Molecular and Cellular Neurosciences
|June 19, 2026
PubMed
Abstract

No abstract available in PubMed .

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Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
Mitochondrial Membranes01:45

Mitochondrial Membranes

A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...

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