Related Experiment Video
Updated: Jun 23, 2026

06:00
Modeling Highly Repetitive Low-level Blast Exposure in Mice
Published on: May 24, 2024
Material parameterization including damage for predicting diver lung underwater explosion (UNDEX) injury.
Srivatsa Bhat Kaudur1, Daniel C Hammerand2, Mohamed Jrad2
1Kevin T. Crofton Department of Aerospace and Ocean Engineering, Virginia Polytechnic Institute and State University, United States of America.
Summary
This study presents a computational model to predict lung injury from underwater explosions (UNDEX). The framework uses anatomical data and material properties to simulate blast effects and quantify damage, aiding safety assessments.
Area of Science:
- Computational mechanics
- Biomedical engineering
- Injury biomechanics
Background:
- Underwater explosions (UNDEX) pose significant risks to human health and marine life.
- Predicting lung injury from blast waves requires sophisticated modeling of complex biological tissues.
- Existing models often lack detailed anatomical representation and accurate material property parameterization.
Purpose of the Study:
- To develop a computational framework for predicting the mechanical response of the lung to UNDEX.
- To create a parameterization methodology for hyperelastic and hyperviscoelastic lung tissue behavior, including damage.
- To enable quantitative assessment of lung injury severity and spatial distribution.
Main Methods:
- Integration of anatomically informed finite-element geometry with constitutive models.
- Parameter identification using literature data, experimental dataset refitting, and plausible value adoption.
- Quantification of injury via mappings from clinical severities to affected lung tissue percentages.
- Incorporation of parameterized damage fields into blast simulations.
Main Results:
- A validated computational framework capable of simulating lung response to UNDEX.
- Methodology for parameterizing lung tissue properties and damage, circumventing direct biological testing.
- Quantitative injury assessment integrated into blast simulations.
Conclusions:
- The developed model provides a robust capability for predicting lung injury from underwater blast events.
- This framework can inform operational protocols, risk assessments, and forensic analyses related to UNDEX.
- The model has potential applications in evaluating environmental impacts, including marine mammal exposure to blast scenarios.
Related Concept Videos
Factors Affecting Pulmonary Ventilation
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Burn Injuries
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
