Related Experiment Video
Updated: Jun 23, 2026

09:17
Ex Utero Electroporation and Organotypic Slice Culture of Mouse Hippocampal Tissue
Published on: March 4, 2015
A Biological Function for the Neuronal Activity-Dependent Component of Bdnf Transcription in the Development of
Neuron
|June 20, 2026
Abstract
No abstract available in PubMed .
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

