Draft Genome Analysis of Delftia tsuruhatensis IICT-RSP4, a Strain with Uricase Potential Isolated from Soil

Delftia tsuruhatensis IICT-RSP4, an uricase producing bacterium was isolated using i-chip method from soil and characterized. Here, we report the draft genome sequence of D. tsuruhatensis IICT-RSP4. The genome data comprised of 6,627,718 bp (6.6 MB) with a GC content of 66.6% with 7 protein encoding genes, 346 sub-systems with 6165 coding sequences and 112 RNAs. The genome revealed five functional secondary metabolite biosynthetic gene clusters viz. terpene, resorcinol, NRP + PKS, T2PKS, and RiPPS related to antimicrobial, anticancer and antimalarial functionality. In vitro, screening studies revealed the uricase potential of the strain D. tsuruhatensis IICT-RSP4 and has been supported by tblastn analysis. This is the first report on the whole genome sequence of an uricase-producing D. tsuruhatensis IICT-RSP4.