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Updated: Jun 23, 2026
In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
Published on: July 19, 2024
Novel Internet Advertising Approach to Raise Public Awareness About Metabolic Dysfunction-Associated Steatotic Liver
Kaori Inoue1,2, Kaoru Araki3,4, Kaoru Shibayama5
1Liver Center, Saga University Hospital Saga Japan.
Background And Aims:
Metabolic dysfunction-associated steatotic liver disease (MASLD), causing cirrhosis and liver cancer, is prevalent worldwide. Analyses of internet searches for "fatty liver" and methods to raise MASLD awareness are needed.
Methods:
We retrospectively analyzed co-occurring terms with "fatty liver" and tracked search histories to identify key terms. In a comparative study, a banner advertisement about MASLD was shown to individuals searching for key terms (key term group: KTG) or regardless of the search terms (control group: CTR). The ad redirected viewers to an educational cartoon, followed by a questionnaire.
Results:
The most frequent co-occurrence term was "how to treat." People searched mainly for lifestyle-related disease and diet terms. Key terms included "diet," "blood sugar level," "cholesterol," "triglyceride," "visceral fat," and "antihypertensive drugs." Banner views were 5 864 184 for KTG and 49 388 176 for CTR. KTG had a higher click-through rate than CTR (0.097% vs. 0.063%; p < 0.001) and more survey responses (3.22% vs. 0.84%; p < 0.001). KTG participants also had a greater intention to seek medical care early (60.2% vs. 42.4%; p = 0.003).
Conclusion:
Search term-based advertising may help increase public awareness of MASLD and may encourage earlier intention to seek medical consultation.
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