Utility of intraoperative 3-dimensional C-arm cone-beam computed tomography for hepatic transarterial
Sunghoon Jeon1, Gahyun Lee1, Jin-Kyung Kim1
1Haemaru Referral Animal Hospital, Seongnam, Republic of Korea.
Introduction:
Hepatic transarterial chemoembolization (TACE) is a palliative treatment option for unresectable hepatic tumors in dogs. Accurate identification of tumor-feeding arteries, including extrahepatic collaterals, is essential for therapeutic efficacy but remains challenging with conventional digital subtraction angiography (cDSA). This study evaluated the feasibility and clinical utility of intraoperative C-arm cone-beam computed tomography (CBCT) during hepatic TACE in dogs compared with conventional mobile C-arm fluoroscopy.
Methods:
This retrospective study included 36 client-owned dogs undergoing hepatic TACE. Dogs were divided into two groups: the CBCT group (n = 18), treated using a ceiling-mounted angiography system with intraoperative CBCT, and the control group (n = 18), treated using a conventional mobile C-arm system. Procedure time, anesthesia time, radiation dose parameters [dose-area product (DAP), air kerma (AK)], contrast medium volume, and the identification of tumor-feeding arteries were compared between the groups.
Results:
Technical success was achieved in all procedures. There were no significant differences in median anesthesia or procedure times between the groups. The median DAP per body weight was significantly lower in the CBCT group than in the control group (p < 0.001), although AK and fluoroscopy time did not differ significantly. While the total contrast medium volume was similar between groups, the volume of contrast medium used specifically for angiography was significantly lower in the CBCT group (p = 0.043). Intraoperative CBCT identified extrahepatic collateral feeding arteries in eight dogs; notably, these vessels were not visualized on preoperative computed tomography in five of these cases.
Conclusion:
Intraoperative C-arm CBCT is a feasible and effective technique for hepatic TACE in dogs. The use of CBCT-derived 3D roadmap guidance enhanced the visualization of vascular anatomy and detection of small extrahepatic collateral vessels while significantly reducing the radiation dose and angiographic contrast medium volume.
