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Encephalitis ll: Pathophysiology

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...

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Updated: Jun 24, 2026

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis

Published on: June 2, 2022

Modeling autoimmune encephalitis with the human hippocampus

Claire D Kim¹, Shuai Wang¹, Dimitris G Placantonakis^1,2,3,4

¹Department of Neurosurgery, New York University Grossman School of Medicine, New York, NY 10016.

Proceedings of the National Academy of Sciences of the United States of America

|June 22, 2026

Summary

No abstract available in PubMed .

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