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Related Experiment Video

Updated: Jun 24, 2026

Building An Open-source Robotic Stereotaxic Instrument

Building An Open-source Robotic Stereotaxic Instrument

Published on: October 29, 2013

StereoPylot: An open-source Raspberry PI-based stereotaxic apparatus controller with 3D printed components for fully

Kirk Mulatz¹, Aiden E Glass¹, McKenna A Bolger¹

¹Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, Saskatoon, SK, S7N 5E5, Canada.

|June 22, 2026

Summary

This summary is machine-generated.

StereoPylot is an open-source, Raspberry Pi-based digital stereotaxic controller that retrofits analog instruments. This system offers motorized control and a user interface to improve accuracy and reduce errors in stereotaxic surgery.

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Area of Science:

Neuroscience
Biomedical Engineering
Open-Source Hardware

Background:

Stereotaxic surgery is crucial for targeted drug delivery and neural circuit research.
Analog stereotaxic instruments are time-consuming and prone to user error due to manual scale reading.
Commercially available digital stereotaxic instruments are expensive and lack customization options.

Purpose of the Study:

To develop an affordable, open-source digital stereotaxic controller for enhanced precision and ease of use.
To provide a customizable solution for neuroscience laboratories performing complex stereotaxic surgeries.
To overcome the limitations of analog instruments and the cost barriers of existing digital systems.

Main Methods:

Developed StereoPylot, an open-source Raspberry Pi-based controller with 3D printed components.
Integrated motorized control for X, Y, and Z axes with variable speed and programmable buttons.
Created a custom graphical user interface for coordinate entry and preset file loading.

Main Results:

StereoPylot enables precise, motorized control of stereotaxic instrument movement.
Demonstrated practical application by quantifying viral expression in rats, with accuracy and precision measurements.
The system is designed for retrofitting onto existing analog stereotaxic manipulators.

Conclusions:

StereoPylot offers a feature-rich, customizable, and cost-effective alternative for stereotaxic surgery.
The open-source design facilitates user customization to meet specific experimental requirements.
This apparatus reduces repetitive motions and calculations, minimizing potential errors in neuroscience research.