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Updated: Jun 24, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis

Jonas Böhnlein1, Johann G Maass2, Julia Dennig3

  • 1Institute of Human Genetics, Heidelberg University Clinic, Heidelberg, Germany; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.

HGG Advances
|June 23, 2026
PubMed

Keywords:
DNA repairHNRNPUHuman Genome Variation SocietycMoMaclustered monoallelic mosaicismdevelopmental and epileptic encephalopathygenetic nomenclaturemonozygotic twinsmosaicismneurodevelopmental disorderpostzygotic mutation

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