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Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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Updated: Jun 24, 2026

Optimizing Mouse Urodynamic Techniques for Improved Accuracy
06:46

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Published on: June 7, 2024

Urodynamic Voiding Patterns in Multiple Sclerosis.

Camille Chesnel1, Nicolas Turmel2, Maelys Teng1

  • 1Sorbonne Université, GRC-01 GREEN, Service de Neuro-urologie, Hôpital Pitié Salpêtrière, Paris, France.

Neurourology and Urodynamics
|June 23, 2026
PubMed
Summary
This summary is machine-generated.

Abnormal voiding patterns, particularly sphincter dysfunction, are common in patients with multiple sclerosis (MS). Current urodynamic indices for diagnosing detrusor underactivity (DUA) and obstruction lack high relevance in this neurogenic population.

Keywords:
detrusor sphincter dyssynergialower urinary tract symptomsmultiple sclerosisneurogenic bladder

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Last Updated: Jun 24, 2026

Optimizing Mouse Urodynamic Techniques for Improved Accuracy
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Published on: June 7, 2024

Real-Time Void Spot Assay
06:39

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Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Area of Science:

  • Urology
  • Neurology
  • Medical Diagnostics

Background:

  • Multiple sclerosis (MS) frequently causes lower urinary tract symptoms.
  • Urodynamic assessment is crucial for understanding voiding dysfunction in MS.
  • Existing diagnostic indices may not accurately reflect the complex voiding patterns in MS.

Purpose of the Study:

  • To characterize urodynamic voiding patterns in patients with MS (PwMS).
  • To evaluate the performance of current nomograms and indices for diagnosing bladder outlet obstruction and detrusor underactivity (DUA).

Main Methods:

  • Cystometry and pressure flow studies were performed on 97 PwMS with lower urinary tract symptoms.
  • Various parameters were used to assess bladder contractility and obstruction, including bladder voiding efficiency (BVE), bladder contractility index (BCI), and bladder outlet obstruction index (BOOI).
  • Agreement between different diagnostic parameters and clinical diagnosis was assessed using weight kappa.

Main Results:

  • Sphincter dysfunction was prevalent (70%), including detrusor sphincter dyssynergia (DSD) and non-relaxing urethral sphincter.
  • Detrusor underactivity (DUA) was identified in 23% of patients.
  • All assessed indices showed only low to moderate agreement with the diagnosis of DUA and obstruction in this cohort.

Conclusions:

  • Abnormal voiding patterns, especially sphincter dysfunction, are frequent in PwMS.
  • Current urodynamic indices for obstruction and DUA are not highly relevant for this specific neurogenic population.
  • Further research is needed to develop more accurate diagnostic tools for voiding dysfunction in MS.