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Nonuniformity in a Certified 68Ge PET Cylinder Phantom: Implications for Normalization Quality Assurance
Subhash Kheruka1, Sana Al-Rashdi2, Naema Al-Maymani2
1Department of Radiology & Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre, University Medical City, Muscat, Oman skheruka@gmail.com.
None:
Quantitative PET imaging depends critically on the accuracy of system normalization and uniformity calibration. We report a manufacturing defect in a certified RadQual 68Ge PET cylinder phantom (BMCY68-2030A-03), a standard reference used for normalization and daily quality control in Siemens Biograph Vision scanners. A localized hot spot was identified within the phantom, producing integral uniformity greater than 8.5% (acceptance limit ≤5%). The nonuniformity was intrinsic to the phantom material and rendered it unsuitable for quantitative use. This finding underscores the importance of independent acceptance testing of long-lived 68Ge standards before clinical deployment to prevent calibration bias and ensure reliable SUV quantification.
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