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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
First-in-Human Mechanical Leaflet Modification of Native Aortic Stenosis During TAVR
Danny Dvir1, Amjad Abu Salman1, Philippe Taieb1
1Jesselson Integrated Heart Center and Eisenberg R&D authority, Share Zedek Medical Center, Jerusalem, Israel; Faculty of Medicine, Hebrew University, Jerusalem, Israel.
JACC. Case Reports
|June 24, 2026
Summary
Mechanical leaflet modification (LM) offers a new solution for preventing coronary obstruction during transcatheter aortic valve replacement (TAVR) in patients with native aortic stenosis. This novel technique shows promise for improving TAVR safety.
Area of Science:
- Cardiovascular Interventions
- Structural Heart Disease
- Interventional Cardiology
Background:
- Coronary obstruction is a critical risk during transcatheter aortic valve replacement (TAVR).
- Mechanical leaflet modification (LM) is established for degenerated bioprostheses but not for native valves.
- Native aortic valve disease presents unique challenges for TAVR procedures.
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