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Related Experiment Video

Updated: Jun 30, 2026

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
12:35

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

Published on: March 17, 2012

ACR Appropriateness Criteria® Myelopathy: 2026 Update.

, Miriam Peckham1, Troy A Hutchins2

  • 1University of Utah Medical Center, Salt Lake City, Utah.

Journal of the American College of Radiology : JACR
|June 24, 2026
PubMed
Summary

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Reply.

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See all related articles
This summary is machine-generated.

Imaging guidelines help diagnose spinal cord dysfunction (myelopathy) by distinguishing between extrinsic and intrinsic causes. These evidence-based criteria aid in selecting appropriate imaging for acute, chronic, and vascular myelopathy.

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Myelopathy, indicating spinal cord dysfunction, requires precise imaging for accurate diagnosis.
  • Differentiating extrinsic and intrinsic spinal cord pathologies is crucial for patient management.
  • Existing imaging evaluation frameworks for myelopathy need to be evidence-based.

Purpose of the Study:

  • To outline evidence-based guidelines for the imaging evaluation of myelopathy.
  • To provide a framework for assessing acute, chronic, and vascular causes of myelopathy.
  • To guide the selection of appropriate imaging to inform surgical or medical interventions.

Main Methods:

  • Utilized the American College of Radiology Appropriateness Criteria framework.
  • Systematic analysis of peer-reviewed medical literature.
Keywords:
AUCAppropriate Use CriteriaAppropriateness Criteriaimagingmyelopathyspinal cordspine

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  • Adapted established methodologies like Grading of Recommendations Assessment, Development, and Evaluation (GRADE).
  • Employed the RAND/UCLA Appropriateness Method for evaluating imaging and treatment procedures.
  • Incorporated expert opinion where literature evidence was lacking or equivocal.

    • Main Results:

    • Developed evidence-based criteria for imaging myelopathy.
    • Established a framework to differentiate between extrinsic and intrinsic pathologies.
    • Provided guidance for evaluating acute, chronic, and vascular etiologies.

    Conclusions:

    • The guidelines offer a structured approach to imaging for myelopathy.
    • These criteria support informed decision-making for surgical and medical interventions.
    • The methodology ensures a robust, evidence-based foundation for clinical practice.