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Delusional parasitosis: 9-year experience from a psychodermatology unit.
E Pérez Zafrilla1, Á González García1, A Grau Echevarría1
1Department of Dermatology, Hospital General Universitario de Valencia, Spain.
Actas Dermo-Sifiliograficas
|June 24, 2026
Summary
Delusional parasitosis (DP) is an underdiagnosed psychiatric disorder with skin symptoms. This study details DP
Area of Science:
- Psychodermatology
- Clinical Psychiatry
- Dermatology
Background:
- Delusional parasitosis (DP), also known as Ekbom syndrome, is a rare psychiatric condition with a dermatological presentation.
- It is frequently underdiagnosed due to limited clinician awareness.
Purpose of the Study:
- To characterize the clinical presentation of delusional parasitosis in a tertiary care setting.
- To identify epidemiological and treatment outcome data for DP patients.
Main Methods:
- A retrospective observational study was conducted.
- Data were collected from 25 patients diagnosed with DP between June 2015 and June 2024.
- Included data: clinical signs, demographics, comorbidities, and treatment outcomes.
Main Results:
- The study identified 25 DP patients (75% female, mean age 55).
- Shared psychotic disorder and positive urine toxicology were noted in 32% of cases.
- The "matchbox sign" was observed in 56% of patients. Antipsychotics, particularly pimozide, were the primary treatment.
- 43% of treated patients showed improvement, with 21.5% achieving complete remission. 44% were lost to follow-up.
Conclusions:
- Delusional parasitosis requires consideration in routine dermatological practice.
- Challenges in managing DP include poor patient adherence and the need for multidisciplinary care.
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