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Updated: Jun 26, 2026
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Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
Published on: April 11, 2012
[Shengqing Jiangzhuo acupuncture method for sepsis-associated gastrointestinal dysfunction: a randomized controlled
Xinyi Xu1, Lu Xiao1, Ying Gao1
1Department of Emergency, First Teaching Hospital of Tianjin University of TCM, Tianjin 300381, China; National Clinical Research Center for Traditional Chinese Medicine, Tianjin 300381.
Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion
|June 25, 2026
Summary
The Shengqing Jiangzhuo acupuncture method effectively improved gastrointestinal function and reduced feeding intolerance in sepsis patients. This approach may work by reducing the body's inflammatory response.
Area of Science:
- Integrative Medicine
- Gastroenterology
- Critical Care
Background:
- Sepsis-associated gastrointestinal dysfunction is a common complication.
- Effective management strategies are crucial for patient outcomes.
Purpose of the Study:
- To evaluate the efficacy and safety of the Shengqing Jiangzhuo acupuncture method for sepsis-induced gastrointestinal dysfunction.
- To explore the potential mechanisms of this acupuncture technique.
Main Methods:
- A randomized controlled trial involving 96 patients with sepsis-associated gastrointestinal dysfunction.
- The observation group received Shengqing Jiangzhuo acupuncture plus conventional treatment; the control group received sham acupuncture plus conventional treatment.
- Outcomes included Acute Gastrointestinal Injury Ultrasonography Score (AGIUS), gastric residual volume (GRV), feeding intolerance, inflammatory markers, and SOFA scores.
Main Results:
- The Shengqing Jiangzhuo group showed significantly lower AGIUS and GRV compared to the control group.
- Patients receiving Shengqing Jiangzhuo acupuncture experienced reduced feeding intolerance and improved caloric intake.
- Inflammatory markers (IL-6, TNF-α, IL-17A, SII, WBC, PCT) were significantly reduced post-treatment in the observation group.
Conclusions:
- The Shengqing Jiangzhuo acupuncture method demonstrates efficacy in improving gastrointestinal function in sepsis patients.
- This acupuncture technique can reduce the incidence of early feeding intolerance.
- The mechanism may involve the modulation of inflammatory responses.
