Related Experiment Video
Updated: Jun 26, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Skeletal-Isomeric Scaffold Design Enables a Dipyrazole[3,4-b;4',3'-e]pyrazine Platform for High-Density Energetic
Wenjin Zhang1, Yi Wang1, Hui Wang1
1School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China.
None:
Here we report a skeletal-isomeric scaffold design strategy for a fused N-heterocyclic energetic platform based on the dipyrazole[3,4-b;4',3'-e]pyrazine scaffold. This framework preserves planarity, symmetry, and π-conjugation while enabling distinct functionalization. On this basis, DNDP and TNDP were synthesized and characterized. TNDP exhibits a density of 1.97 g·cm-3, a decomposition temperature of 201 °C, and calculated detonation performance of 9501 m·s-1 and 41.1 GPa. The delocalized backbone offsets dense nitro groups, ensuring thermal robustness and high performance.
More Related Videos
14:11Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
07:20Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods
Published on: October 6, 2023
Related Concept Videos
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry
[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement
Five-Membered Heterocyclic Aromatic Compounds: Overview
Hybridization of Atomic Orbitals II