Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

Comparing the effect of multi-gradient echo and multi-band fMRI during a semantic task.

Ajay D Halai¹, Richard N Henson^1,2, Paola Finoia¹

¹MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom.

Imaging Neuroscience (Cambridge, Mass.)

|June 25, 2026

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predictions and declarative memory encoding: two fMRI paradigms provide slim pickings for SLIMM.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026

Same author

Stable individual differences dominate adult brain volume variation until later life.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Genetic risk of Alzheimer's disease is associated with loss of brain network segregation in midlife.

Communications biology·2026

Same author

All spectral frequencies of neural activity reveal semantic representation in the human anterior ventral temporal cortex.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Multi-Centre Reproducibility of DTI and NODDI in White Matter Tracts Segmented Using TractFinder Across Three MRI Scanners of the Same Model.

Human brain mapping·2026

Same author

Dissociable contributions of cortical thickness and surface area to cognitive ageing: evidence from multiple longitudinal cohorts.

bioRxiv : the preprint server for biology·2026

Multi-echo and multi-band functional magnetic resonance imaging (fMRI) improve signal detection, especially in brain regions with susceptibility artifacts. Combining these techniques offers a promising default for fMRI, enhancing sensitivity for various analyses.

Area of Science:

Neuroimaging
Cognitive Neuroscience
Magnetic Resonance Imaging

Background:

Blood oxygenation level dependent (BOLD) signal sensitivity in fMRI varies across brain regions due to magnetic susceptibility artifacts.
Ventral anterior temporal lobes, crucial for semantic cognition, show reduced fMRI sensitivity with conventional protocols.
Multi-echo fMRI enhances BOLD contrast-to-noise but can compromise sequence parameters.

Purpose of the Study:

To investigate the independent and interactive effects of multi-echo and multi-band fMRI on sensitivity across the brain.
To assess the impact of these techniques on univariate and multivariate analyses for detecting semantic activation and patterns.
To evaluate the potential of combining multi-echo and multi-band fMRI for improved neuroimaging.

Main Methods:

Keywords:

BOLD fMRI multi-band multi-echo semantic cognition slice leakage

More Related Videos

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Published on: July 6, 2011

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

Related Experiment Videos

Last Updated: Jun 26, 2026

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Published on: July 6, 2011

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

Factorial design manipulating the number of echoes and/or bands in fMRI acquisition.
Assessment of activation detection precision (T-statistics) and magnitude.
Evaluation of multi-voxel pattern detection and decoding performance.
Application of independent component analysis (ICA)-denoising to multi-echo data.

Main Results:

Multi-band protocols improved activation detection precision without signal leakage.
Multi-echo protocols enhanced BOLD signal in susceptibility artifact-prone regions like temporal lobes.
Both multi-banding and ICA-denoising improved multi-voxel decoding.
Multi-echo protocols reduced signal magnitude in medial temporal lobes, potentially due to acceleration.

Conclusions:

The combined multi-echo, multi-band fMRI protocol is a promising default for most brain regions, particularly those affected by susceptibility artifacts.
This approach enhances sensitivity for both univariate and multivariate analyses.
Future applications can leverage increased resolution and advanced denoising techniques for improved fMRI studies.