Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

Published on: May 5, 2023

Ion-Selective Sensors for Orthopaedic Applications: A Systematic Review.

Giorgia Polidori¹, Andrea Visani², Gianluca Giavaresi²

¹Department of Information Engineering, University of Brescia, Via Branze 38, 25123 Brescia, Italy.

|June 25, 2026

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Circulating and Tissue Biomarkers Associated with Disease Severity and Progression in Adolescent Idiopathic Scoliosis: A Systematic Review.

Cells·2026

Same author

Coevolution of NK and Tumor Cell States Along Multiple Myeloma Progression from Precursor Conditions.

International journal of molecular sciences·2026

Same author

Advanced Mathematical Platform for the Control and Manipulation of Magnetized Living Cells.

Bioengineering (Basel, Switzerland)·2026

Same author

Aerosol Jet Printed Ion-Selective Electrodes for Potassium Detection.

Sensors (Basel, Switzerland)·2026

Same author

Platelet-Rich Plasma vs. Mesenchymal Stem Cells for Lumbar Disc Degeneration: A Systematic Review and Meta-Analysis.

International journal of molecular sciences·2026

Same author

Clinical Characteristics, Surgical Management and Outcomes of Sciatic Scoliosis Secondary to Lumbar Disc Herniation: A Systematic Review.

Life (Basel, Switzerland)·2026

Ion-selective sensors (ISSs) show promise for orthopaedic diagnostics and treatment, though their clinical application is still underdeveloped. Further research is needed to overcome challenges like biocompatibility and long-term stability for ISSs in musculoskeletal applications.

Area of Science:

Biomedical Engineering
Materials Science
Orthopaedic Surgery

Background:

Ion-selective sensors (ISSs) offer advanced capabilities like miniaturization and high specificity.
While ISSs are studied in environmental and general health, their specific role in orthopaedics remains largely unexplored.
Technological advancements are driving the potential of ISSs in medical diagnostics and prevention.

Purpose of the Study:

To review the current state and future potential of ion-selective sensors (ISSs) specifically within the field of orthopaedics.
To identify key ions targeted by ISSs that are relevant to musculoskeletal pathophysiology.
To evaluate technological solutions and highlight development targets for clinical orthopaedic applications of ISSs.

Main Methods:

Keywords:

biocompatible ion-selective sensors orthopaedic monitoring osteointegration prosthetic implants wearable

More Related Videos

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Published on: July 15, 2009

Related Experiment Videos

Last Updated: Jun 26, 2026

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

Published on: May 5, 2023

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Published on: July 15, 2009

Systematic literature search of PubMed and Scopus databases.

Keywords included "ion", "sensor", "electrodes", "selective", "musculoskeletal", "implant", "joint replacement", and "orthopaedic".

Screening and synthesis of 44 relevant studies, classifying them by target ion and evaluating technological aspects.

Main Results:

Few studies specifically address ISS applications in orthopaedics, indicating a significant research gap.
All investigated ISSs targeted ions relevant to musculoskeletal pathophysiology, suggesting broad potential.
Key challenges for clinical translation include biocompatibility, long-term stability, calibration, and validation.

Conclusions:

ISSs represent a largely untapped frontier in orthopaedics with potential for diagnosis and treatment.
Addressing challenges in biocompatibility and stability is crucial for transitioning ISSs from prototypes to clinical tools.
Successful development of ISSs will enable advanced sensorised orthopaedic devices and personalized medicine.