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Updated: Jun 27, 2026

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
09:51

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

Published on: May 18, 2018

Rab27 a regulates dendritic cell immune tolerogenic capacity

Yang-Peng Wu, Shu-Wang Peng, Dong Hua Bin

    International Archives of Allergy and Immunology
    |June 25, 2026
    PubMed
    Summary

    Rab27a activation is crucial for dendritic cells to secrete interleukin-10 (IL-10) and maintain immune tolerance. Defects in this pathway, regulated by MADD, contribute to food allergy and may offer therapeutic targets.

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