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Published on: December 6, 2016
Risk factors for residual obstructive sleep apnea after adenotonsillectomy in children: A single-center retrospective
Jianbin Zhang1, Yufeng Zhang2, He Li1
1Department of Otolaryngology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, 441021, China.
Insights
Residual obstructive sleep apnea (OSA) is common after adenotonsillectomy (T&A) in children. Obesity, severe baseline OSA, and asthma are key predictors of incomplete recovery, necessitating careful preoperative counseling and follow-up.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Respiratory Medicine
Background:
- Adenotonsillectomy (T&A) is the primary treatment for pediatric obstructive sleep apnea (OSA).
- A significant number of children experience residual OSA post-T&A, particularly those with specific clinical presentations.
- Identifying preoperative predictors of residual OSA is vital for patient management and expectation setting.
Purpose of the Study:
- To identify preoperative risk factors associated with residual obstructive sleep apnea (OSA) in children following adenotonsillectomy (T&A).
- To improve the understanding of factors contributing to treatment failure in pediatric OSA.
Main Methods:
- Retrospective analysis of 642 children (aged 3-14 years) who underwent T&A for OSA.
- Inclusion of complete preoperative and postoperative polysomnography (PSG) data (6-12 months post-surgery).
- Logistic regression analysis to determine independent risk factors for residual OSA (defined as AHI ≥ 2 events/h).
Main Results:
- Overall residual OSA prevalence was 26.8% (172/642 children).
- Independent risk factors identified: obesity (OR 3.12), severe baseline AHI (OR 1.08 per unit increase), and concurrent asthma (OR 1.95).
- Multivariate risk assessment showed strong predictive capability (AUC = 0.82).
Conclusions:
- Residual OSA is prevalent in approximately one-quarter of pediatric patients post-T&A.
- Obesity, severe baseline disease, and comorbid asthma are significant predictors of incomplete OSA resolution.
- Targeted preoperative counseling and postoperative PSG surveillance are recommended for high-risk pediatric OSA patients.
Objective:
Adenotonsillectomy (T&A) is the first-line treatment for pediatric obstructive sleep apnea (OSA). However, a significant proportion of children, particularly those with specific phenotypes, exhibit residual OSA postoperatively. Identifying preoperative risk factors for residual disease is crucial for managing parental expectations and planning postoperative care.
Methods:
This single-center retrospective study included children (aged 3-14 years) who underwent T&A for OSA between January 2018 and December 2024. All patients had complete preoperative and postoperative (6-12 months) polysomnography (PSG) data. Residual OSA was defined as a postoperative obstructive apnea-hypopnea index (AHI) ≥ 2 events/h. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors.
Results:
A total of 642 children were included. The overall prevalence of residual OSA was 26.8% (172/642). The multivariate analysis identified three independent risk factors: obesity (BMI ≥ 95th percentile) [Odds Ratio (OR) 3.12, 95% CI 1.85-5.26], severe baseline AHI (OR 1.08 per unit increase, 95% CI 1.05-1.11), and concurrent asthma (OR 1.95, 95% CI 1.12-3.40). The multivariate risk assessment demonstrated good discrimination with an area under the curve (AUC) of 0.82 (95% CI 0.78-0.86).
Conclusion:
Residual OSA is common after T&A, affecting approximately one-quarter of the pediatric population. Obesity, disease severity, and comorbid asthma are robust risk factors of incomplete resolution. Preoperative counseling and planned postoperative PSG surveillance are essential for these high-risk groups.
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