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Updated: Jun 27, 2026

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
Published on: April 30, 2021
OpenIO: An open framework for AI-native immunotherapy
Yingcheng Wu1, Hao Xiao1, Nan Jiang1
1Department of Hepatobiliary Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; State Key Laboratory of Genetics and Development of Complex Phenotypes; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education; Institutes of Biomedical Sciences; National Engineering Center for Immunotherapy; Human Phenome Institute, Fudan University; Shanghai Academy of Natural Sciences, Shanghai, China.
Abstract:
We propose Open Immune Oncology (OpenIO), a framework integrating generative AI and omics to advance precision oncology. By leveraging biological scaling laws and foundation models, we aim to transition immunotherapy from empirical screening to rational, AI-native engineering of therapeutic interventions.
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