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Published on: July 12, 2018
A Brief Overview of Colitis Cystica Profunda and Potential Animal Models
Alfonso S Gozalo1, William R Elkins1
1Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
Abstract:
Colitis cystica profunda (CCP) is a rare benign lesion in humans that can mimic, clinically and radiologically, a malignant neoplasm. CCP etiopathogenesis is poorly understood and believed to be due to congenital ectopia or associated with chronic inflammation. Despite sporadic reports of CCP in animals, there are no established animal models for the study of this disease. Here, we briefly review CCP in humans and animals with a discussion of the possible etiopathogenesis and potential animal models.
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