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Published on: November 30, 2022
LTM-UNet: Linear Transformer-Mamba with Attention-Based U-Net for Context-Aware Breast Ultrasound Image Segmentation
Shivpratap Singh Kushwah1,2, Santosh Prakash Chouhan1,2, Narinder Singh Punn1,2
1Department of Information Technology, Atal Bihari Vajpayee Indian Institute of Information Technology and Management, Gwalior 474015, MP, India.
Diagnostics (Basel, Switzerland)
|June 26, 2026
Summary
A new deep learning model, LTM-UNet, improves breast lesion segmentation in ultrasound images by combining transformer-based encoding and state-space decoding. This approach enhances both global context and fine details for more accurate results.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computer Vision
Background:
- Accurate breast lesion segmentation is crucial for diagnosis.
- Existing deep learning models struggle with global context and fine details.
Purpose of the Study:
- To develop a novel segmentation model for improved context-aware dense segmentation of ultrasound images.
- To address limitations in current deep learning approaches for medical image analysis.
Main Methods:
- Proposed LTM-UNet, integrating a vision transformer encoder with a state-space model decoder in a U-Net framework.
- Utilized attention-guided skip-fusion to preserve spatial details and minimize the semantic gap.
- Employed a direction-aware decoder for efficient long-range dependency capture.
Main Results:
- LTM-UNet achieved a Dice score of 82.41% on the BUSI dataset and 86.62% on Dataset B (UDIAT).
- The model outperformed existing segmentation methods in Dice score and Intersection-over-Union (IoU) metrics.
- Demonstrated effectiveness on benchmark ultrasound medical imaging datasets.
Conclusions:
- LTM-UNet effectively captures structural details and contextual information for superior segmentation performance.
- The integration of transformer encoding, attention fusion, and state-space decoding enhances segmentation accuracy.
- The proposed method offers a promising advancement in automated breast lesion analysis.

