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Updated: Jun 27, 2026

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
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Published on: December 29, 2023

Exercise Training Regulates Cortical GPCR-Mediated Signaling Networks Through cAMP, Calcium, and Neuroactive

Yin-Yu Chiang1, Michael Anekson Widjaya2, Shin-Da Lee3

  • 1PhD Program for Health Science and Industry, China Medical University, Taichung 406040, Taiwan.

International Journal of Molecular Sciences
|June 26, 2026
PubMed
Summary

Exercise training impacts brain G-protein coupled receptor (GPCR) pathways in diabetic obesity. This study reveals exercise-induced changes in cAMP and calcium signaling pathways in the cerebral cortex of diabetic rats.

Keywords:
G protein-coupled receptorscAMPcalcium signalingcerebral cortexdiabetesneuroactive ligand–receptor interactionobesityphysical trainingtranscriptomics

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