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Related Concept Videos

Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

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Related Experiment Video

Updated: Jun 27, 2026

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
05:38

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B

Published on: January 30, 2017

Routine Troponin I Assessment Enhances Risk Stratification in Hospitalized Patients with Seasonal Influenza.

Tobias Harm1, Johannes Gernert1, Monika Zdanyte1

  • 1Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.

Journal of Clinical Medicine
|June 26, 2026
PubMed
Summary
This summary is machine-generated.

Myocardial injury, indicated by high-sensitivity troponin I (hsTnI), predicts poor outcomes in hospitalized influenza patients. Routine hsTnI testing improves risk assessment for better patient management.

Keywords:
cardiac injurycardiovascular riskcoronary artery diseasehigh-sensitive troponin Iinflammationinfluenzamachine learningrisk stratification

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High-throughput Detection Method for Influenza Virus
10:05

High-throughput Detection Method for Influenza Virus

Published on: February 4, 2012

Related Experiment Videos

Last Updated: Jun 27, 2026

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
05:38

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B

Published on: January 30, 2017

High-throughput Detection Method for Influenza Virus
10:05

High-throughput Detection Method for Influenza Virus

Published on: February 4, 2012

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Biomarkers

Background:

  • Myocardial injury is associated with adverse outcomes in patients with respiratory infections.
  • Seasonal influenza hospitalization presents a significant clinical challenge.

Purpose of the Study:

  • To assess the prognostic value of high-sensitivity troponin I (hsTnI) in predicting 30-day outcomes for hospitalized influenza patients.
  • To determine if hsTnI can improve risk stratification beyond conventional scores.

Main Methods:

  • A retrospective analysis of 277 adult patients with laboratory-confirmed influenza.
  • Myocardial injury defined by elevated hsTnI levels.
  • Primary composite endpoint: 30-day mortality, ICU admission, and mechanical ventilation.

Main Results:

  • Patients with myocardial injury showed significantly higher rates of the composite endpoint (p < 0.0001).
  • Dynamic hsTnI elevations correlated with worse outcomes (p = 0.026).
  • Machine learning models using hsTnI achieved excellent predictive performance (AUC = 0.99), outperforming standard scores (p < 0.0001).

Conclusions:

  • Myocardial injury, identified by hsTnI, is a strong predictor of short-term adverse outcomes in hospitalized influenza patients.
  • Routine hsTnI assessment enhances risk stratification, aiding early identification and management of high-risk individuals.