Dose-Response Effect of Oral Caffeine Use on Aerobic Exercise Performance: A Systematic Review and Meta-Analysis.

Gabriel L Martins1,2, Juliana M Aparecido3, Marcelo L Marquezi3

  • 1Plenitude Education Institute, Sao Paulo 01409-000, SP, Brazil.

Nutrients
|June 26, 2026
PubMed
Summary

Caffeine supplementation enhances endurance performance by reducing time-trial completion times. Low to moderate doses (1.3-6 mg·kg-1) show significant ergogenic effects, with moderate doses offering more consistent benefits.

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