A Case Report of Condylomata Lata, an Unsual Manifestation of Syphilis in The Western World

A 62-year-old caucasian male with an intellectual disability was referred due to two exophytic, pediculated, non-infiltrated perianal lesions of reddish-pink colour, surrounded by ten hyperpigmented brown macules in the gluteal area (figure 1). No relevant prior history was available. Histology showed marked acanthosis with surface erosion and exuberant neutrophil exocytosis; a dense plasmocytic inflammatory infiltrate was present (figure 2). Serological testing showed increased anti-treponemic IgG and IgM titers and RPR title of 1:128. Condylomata lata is a rare clinical manifestation of secondary syphilis consisting of pinkish or hypopigmented papules or plaques in the anogenital area. They are extremely infectious, and their recognition enables prompt diagnosis and effective therapy, with excellent prognosis.