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Updated: Jun 28, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Patient-Centered Approaches to Non-Muscle-Invasive Bladder Cancer Care
Melinda Z Fu1, Jennifer Sykes1, John Pfail1
1Division of Urology, Department of Surgery, Rutgers Cancer Institute, New Brunswick, NJ, USA.
Abstract:
Approximately 75% to 80% of cases are nonmuscle-invasive bladder cancer (NMIBC), an often chronic condition with high recurrence rates necessitating lifelong surveillance and repeated interventions. Despite contemporary favorable 5-year cancer-specific survival ranging from 71% to 96%, patients experience substantial physical, psychological, and financial burdens due to the significant and invasive follow-up monitoring and treatment of recurrences. TURBT and adjuvant intravesical therapy remain the cornerstone of treatment of NMIBC, and we discuss some innovations within this space, with novel agents and new techniques. Further, we focus on symptom management for patients undergoing therapy and enhancing bladder cancer survivor's quality of life.
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