Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

Diseases of the Liver and Gallbladder

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Root Cause Analysis In Ensuring Patients Safety: A Narrative Review.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

Intraoperative Adverse Event Reporting in Gastrointestinal Cancer Surgery: A Narrative Review on the Application of ClassIntra.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

Ethnobotany of desert medicinal plants and their sustainable ethnomedicinal utilization.

Die Naturwissenschaften·2026

Same author

Isolated Hepatic Tuberculosis Masquerading as Hepatic Cystadenoma: A rare presentation.

Pakistan journal of medical sciences·2026

Same author

Impact of fungal biliary colonization on postoperative outcomes following pancreaticoduodenectomy: A systematic review.

Pakistan journal of medical sciences·2026

Same author

Prevalence and Factors Associated With Financial Toxicity Among Patients With GI Cancer in Pakistan.

JCO global oncology·2026

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

From Morbidity & Mortality To Textbook Outcomes - The Evolution Of Quality Assessment In Liver Surgery: Perspective

Saleema Begum¹, Muhammad Rizwan Khan¹

¹Aga Khan University, Hospital, Karachi, Pakistan.

JPMA. the Journal of the Pakistan Medical Association

|June 27, 2026

Summary

Textbook outcomes offer a comprehensive measure for liver surgery quality, surpassing traditional metrics. This novel approach ensures better patient care and safety by evaluating multiple perioperative factors for hepatectomy-specific complications.

Keywords:

Liver surgery, Textbook outcomes, Patients safety.

More Related Videos

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

Published on: January 19, 2024

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation

Published on: May 16, 2025

Related Experiment Videos

Last Updated: Jun 28, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

Published on: January 19, 2024

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation

Published on: May 16, 2025

Area of Science:

Hepatobiliary Surgery
Surgical Quality Assessment
Patient Safety

Background:

Traditional liver surgery quality assessment relies on individual outcomes like morbidity and mortality.
Existing tools may not adequately address hepatectomy-specific complications in liver surgery.
A holistic approach is needed for comprehensive quality assurance in liver surgery.

Purpose of the Study:

To evaluate the concept of "textbook outcome" in liver surgery.
To discuss the application of textbook outcome as a quality assessment tool.
To highlight the importance of multifaceted outcome measures in hepatectomy.

Main Methods:

The "textbook outcome" for liver surgery was developed using a modified Delphi method.
The development process occurred between July 2020 and October 2021.
This review evaluates the concept and its application in Pakistan.

Main Results:

"Textbook outcome" is a novel composite measure for desirable surgical outcomes in liver surgery.
It incorporates multiple perioperative parameters for a holistic patient care perspective.
This established tool provides procedure-specific information for quality assurance.

Conclusions:

"Textbook outcome" offers a superior, comprehensive quality indicator for liver surgery compared to traditional methods.
Its application is crucial for enhancing patient safety and ensuring quality in hepatectomy.
The review discusses the relevance and implementation of this tool in the context of Pakistan.