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Post-Operative Infection in Rhinoplasty With Autologous Versus Cadaveric Costal Cartilage Grafting
Lillian W Dattilo1, Leillani L Ha2, Robin W Lindsay1
1Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye & Ear, Boston, Massachusetts, USA.
The Laryngoscope
|June 28, 2026
Summary
Post-operative infection rates after rhinoplasty using autologous versus cadaveric rib grafts were similar. Prophylactic antibiotics did not reduce infection risk in these rhinoplasty patients.
Area of Science:
- Plastic Surgery
- Otolaryngology
- Surgical Infection Control
Background:
- Rhinoplasty often utilizes costal cartilage grafts for reconstruction.
- The choice between autologous (patient's own) and allogeneic (cadaveric) grafts involves different considerations.
- Understanding infection risks associated with graft type and antibiotic use is crucial for patient outcomes.
Purpose of the Study:
- To compare post-operative infection rates in rhinoplasty patients receiving autologous versus irradiated cadaveric costal rib grafts.
- To evaluate the efficacy of prophylactic antibiotics in reducing infection rates in these patient groups.
Main Methods:
- Retrospective review of 707 patients undergoing rhinoplasty with costal cartilage grafting (2002-2025).
- Comparison of infection rates between autologous and irradiated cadaveric rib graft groups.
- Analysis of post-operative antibiotic use and return to operating room for revision.
Main Results:
- No significant difference in infection rates between autologous (2.3%) and cadaveric (2.3%) rib grafting groups (p=0.99).
- One patient (0.34%) in the cadaveric group required revision surgery for infection.
- Prophylactic antibiotics did not significantly decrease post-operative infection rates in either group.
Conclusions:
- Autologous and irradiated cadaveric costal rib grafts demonstrate comparable post-operative infection rates in rhinoplasty.
- Prophylactic antibiotic use does not appear to lower the risk of infection following rhinoplasty with costal cartilage grafting.
