Related Experiment Video
Updated: Jun 30, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Artificial intelligence (AI)-assisted full-course case management for primary liver cancer: System design,
Yanhui Wang1, Xian Yue1, Ruishuang Zheng1
1Department of Hepatobiliary Cancer, Tianjin Medical University Cancer Hospital and Institute, National Clinical Research Centre for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Centre for Cancer, Tianjin, China.
None:
Primary liver cancer presents substantial management challenges across the surgical trajectory, including high recurrence rates, prolonged rehabilitation, and fragmented post-discharge care. This correspondence presents a multidisciplinary physician-nurse co-led, artificial intelligence (AI)-assisted full-course case management model grounded in just-in-time adaptive intervention (JITAI) theory. The model spans four phases-peri-admission, perioperative, post-discharge home-based care, and long-term follow-up-supported by an intelligent platform enabling automated decision triggering, symptom monitoring, tailored health education, and intervention matching. A pilot study with 25 patients was conducted from March to May 2026 at a tertiary cancer hospital in Tianjin, China. Preliminary results revealed improvements in antiviral medication adherence (80-96%), targeted therapy adherence (96-100%), and satisfaction (99.8%), with reductions in missed follow-ups and symptom reporting delays. Multicenter controlled studies need to be conducted to evaluate this model's effectiveness, cost-effectiveness, and long-term sustainability.
