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Operation of the Collaborative Composite Manufacturing (CCM) System
Published on: October 1, 2019
ctxR: Utilities for interacting with the CTX APIs
Paul M Kruse1,2, Caroline L Ring1, Katie Paul Friedman1
1United States Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, P.O. Box 12055, Research Triangle Park, 27709, NC, United States of America.
Abstract:
A new R package, ctxR, is presented. ctxR is an open-source R Client package used to interact with the Computational Toxicology and Exposure Application Programming Interfaces (CTX APIs) in R. The CTX APIs were developed by the US EPA's Center for Computational Toxicology and Exposure, and provide users transparent, reproducible access in a programmatic manner to the data surfaced on the CompTox Chemicals Dashboard (CCD) and other data sources. The utility of this package is demonstrated through a case study that compares traditional Points of Departure (PODs) and PODs based on New Approach Methods (NAMs), referred to as PODNAM, relative to estimates of external exposure as an indicator of level of risk. This analysis combines a wide variety of data and showcases the power of programmatic data access that ctxR can provide to the scientific community.
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