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Related Experiment Video

Updated: Jun 30, 2026

Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting
10:36

Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting

Published on: December 9, 2022

Fiber-reinforced hydrogels: From multiscale structural design to advanced engineering applications.

Bingtao Li1, Anzhu Peng1, Xinting Dong1

  • 1MOE Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Biointerphases
|June 29, 2026
PubMed
Summary

Fiber-reinforced hydrogels mimic natural tissues, enhancing mechanical strength and toughness. This review covers fiber types, interface interactions, preparation methods, and applications in medicine and electronics.

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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

Area of Science:

  • Materials Science
  • Polymer Science
  • Biomaterials Engineering

Background:

  • Hydrogels are polymer networks with high water content, mimicking soft tissues.
  • Traditional hydrogels suffer from low mechanical strength, poor toughness, and fatigue susceptibility.
  • Natural soft tissues offer inspiration for enhancing hydrogel mechanical properties through fibrous reinforcement.

Purpose of the Study:

  • To review the advancements in fiber-reinforced hydrogels.
  • To explore various reinforcing fibers and their interfacial interactions with hydrogel matrices.
  • To summarize preparation techniques and discuss applications and future challenges.

Main Methods:

  • Review of literature on fiber-reinforced hydrogels.
  • Categorization of reinforcing fibers (natural, synthetic, inorganic, carbon-based).
  • Analysis of interfacial interactions (physical entanglement, noncovalent, covalent bonds).
  • Summary of preparation methods (in situ infiltration, directional freezing, 3D printing).

Main Results:

  • Fiber reinforcement significantly improves hydrogel mechanical strength, toughness, and fatigue resistance.
  • Diverse fiber types and interfacial interactions offer tunable properties.
  • Established preparation methods enable controlled fabrication of fiber-reinforced hydrogels.
  • Successful applications demonstrated in medicine, sensing, and wearable devices.

Conclusions:

  • Fiber-reinforced hydrogels present a promising solution to overcome the limitations of traditional hydrogels.
  • Precise interface regulation and scalable manufacturing are key areas for future development.
  • These advanced hydrogels hold significant potential for next-generation biomedical and electronic devices.